In partnership with the Health Resources and Services Administration, Si Se Puede II increases prevention, treatment, and recovery services in Pinal County. Si Se Puede II expands best practices, culturally responsive opioid use prevention education; intensifies treatment outreach efforts; co-locates probation/parole services with treatment services; facilitates community-based Naloxone distribution and improves delivery of telehealth counseling. The Si Se Puede Consortium fosters equitable and sustainable collaborations among agency members to combat the opioid and substance use disorders epidemic within the communities. The consortium works closely with local partners engaging in community mobilization efforts to shift norms surrounding substance use, especially among vulnerable populations.